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Product Details:
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| Molecular Weight: | 245.20 | Appearance: | White To Off-white Powder |
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| Storage: | -20℃ | Molecular Formula: | C9H12FN3O4 |
| CAS Number: | 144089-97-4 | Purity: | HPLC ≥98% |
| High Light: | Phosphoramidite DNA 10212-20-1,Deoxycytidine Phosphoramidite DNA,Phosphoramidite 10212-20-1 |
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2'-F-dC/2'-fluoro-2'-deoxycytidine/C9H12FN3O4HPLC ≥98%/CAS No. 10212-20-1
| Appearance | White to off-white powder |
| Weight loss on drying detection |
≤0.5% |
| Purity (HPLC) | ≥98% |
Biological activity of 2 '- deoxy-2-fluorocytidine:
| describe | 2'-Deoxy-2'-fluorocytidine is a nucleoside analogue,is an effective inhibitor of replication of Congo hemorrhagic fever virus (CCHFV).2 '- Deoxy-2' - fluorocytidine can cooperate with T705 to enhance the antiviral effect of the two compounds on CCHFV replication. |
| Related categories | Signal pathway>>Anti infection>>Influenza virus>>Research field>>Infection |
| In vitro study | 2 '- deoxy-2' - fluorocytidine has antiviral activity. The effective concentrations (EC50) of 2 '- deoxy-2' - fluorocytidine against CCHFV and CCHFV/ZsG in Huh7 cells are 61 nm and 31 nm, respectively. 50% cytotoxicity concentration (CC50)>50.0 μ M is in Huh7 cells. |
| storage | Please store the product under the recommended conditions in the analysis certificate. |
| transport | room temperature |
| SMILES | F[C@H]1[C@@](N2C(N=C(C=C2)N)=O)([H])O[C@@H]([C@H]1O)CO |
| 4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one Usage And Synthesis |
| Chemical Properties | White Solid |
| Uses | 2'-Deoxy-2'-fluorocytidine is a potent inhibitor of the subgenomic hepatitis C virus replicon in Huh-7 cells. 2'-Deoxy-2'-fluorocytidine has been shown to inhibit Borna Disease virus replication and s pread. |
| 2 '- Deoxy-2' - fluorocytidine is a nucleoside analogue and an effective inhibitor of replication of Congo hemorrhagic fever virus (CCHFV). 2 '- Deoxy-2' - fluorocytidine can cooperate with T705 to enhance the antiviral effect of the two compounds on CCHFV replication. |
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