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Product Details:
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| Brand Name:: | HUANA | CAS No.: | 98796-51-1 |
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| Storage: | -20℃ | Application: | Oligonucleotide Synthesis |
| Appearance: | White To Pale Yellow Crystalline Powder | Purity: | HPLC ≥99% |
| High Light: | Thymidine Nucleoside Phosphoramidite,GMP Nucleoside Phosphoramidite,5'-O-DMT-thymidine 3'-CE phosphoramidite |
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| CAS No | [98796-51-1] |
| Synonyms | dT-CE phosphoramidite 5'-Dimethoxytrityl-2'-deoxythymidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite |
| Product Code | C-015 |
| MDL No | MFCD00055063 |
| Chemical Formula | C40H49N4O8P |
| Molecular Weight | 744.83 g/mol |
| Smiles | CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OP(N(C(C)C)C(C)C)OCCC#N |
| Storage | store at <-20°C |
5'-O-DMT-thymidine 3'-CE phosphoramidite is a building block for the introduction of thymidine units into oligonucleotides. 5'-O-DMT-thymidine 3'-CE phosphoramidite is utilised in a broad range of applications, including the synthesis of natural and unnatural DNA and RNA strands. Phosphoramidites are the reagent class of choice for oligonucleotide synthesis as they contain readily removable orthogonal protecting groups and can be produced at reasonable scales. The diisopropylamino leaving group is readily cleaved upon exposure to an azole catalyst allowing for a highly efficient coupling reaction with a free hydroxyl group on the growing oligonucleotide and oxidation of the subsequent phosphite triester, followed by beta-elimination of the cyanoethyl group affords the stable phosphodiester linkage.
5'-O-DMT-thymidine 3'-CE phosphoramidite
Product Code: C-015
Synonyms: dT-CE phosphoramidite 5'-Dimethoxytrityl-2'-deoxythymidine, 3'-[(2-cyanoethyl)-(N,Ndiisopropyl)]-phosphoramidite
CAS Number: 98796-51-1
Chemical Formula: C40H49N4O8P
Molecular Weight: 744.83
Appearance: White to pale yellow crystalline powder
Purity (HPLC): min 99%
Identity ( 31P NMR): Conforms to structure
Contact Person: Lara He
Tel: +86 15900695956
