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Product Details:
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| High Light: | 99%Min RNA Phosphoramidites,RNA Phosphoramidites 104992-55-4,phosphoramidite synthesis 104992-55-4 |
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98%Min N6-Bz-5'-O-DMT-2'-O-TBDMS-A-CE RNA Phosphoramidites Synthesis CAS 104992-55-4
Product name: N6-Bz-5'-O-DMT-2'-O-TBDMS-A-CE
Purity: 98%min
CAS No.: 104992-55-4
| Purity (HPLC) | ≥98% |
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Purity (31P NMR) |
≥98% |
| Solvent Residue (GC) |
≤3.0%w/w |
| Water Content |
≤0.2%w/w |
RNA phosphoramidites, along with RNA CPG, and analogous to DNA synthesis support the synthesis of sequence-specific RNA oligonucleotides for RNA interference (RNAi) and can be used in target validation and other drug development techniques. Modern phosphoramidite-mediated synthesis has enabled routine high-yielding preparations of RNA oligonucleotides. High-quality RNA phosphoramidites are key to low failure rates, the high biological activity of synthesis products, and cost-effectiveness.
Key Features
Industry-standard 2′O-TBDMS protective group
Consistent lot-to-lot purity and performance
Compatible with deprotection methods based on methylamine or AMA
Standard RNA phosphoramidites provide excellent coupling results when used with ETT or BTT as an activator; best results are obtained with activator 42
Capping with standard acetic anhydride capping reagent rather than with fast Deprotection Cap A
Manufactured under a certified ISO 9001 quality system
DMT-2′O-TBDMS-rA(bz) Phosphoramidite is configured for ÄKTA and OligoPilot Synthesizers.
Contact Person: Lara He
Tel: +86 15900695956
